Assessing DNA damage from enzyme-oxidized single-walled carbon nanotubes
نویسندگان
چکیده
منابع مشابه
Assessing DNA Damage from Enzyme-Oxidized Single-Walled Carbon Nanotubes.
Peroxidase enzyme digests of oxidized single-wall carbon nanotubes (SWCNT) were shown to damage DNA in potentially genotoxic reactions for the first time using an electro-optical array with and without metabolic activation.
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We present here the use of amino-terminated DNA strands in functionalizing the open ends and defect sites of oxidatively prepared single-walled carbon nanotubes, an important first step in realizing a DNA-guided self-assembly process for carbon nanotubes.
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Single-walled carbon nanotubes (SWCNTs) are hollow, long cylinders with extremely large aspect ratios, made of one atomic sheet of carbon atoms in a honeycomb lattice. They possess extraordinary thermal, mechanical, and electrical properties and are considered as one of the most promising nanomaterials for applications and basic research. This chapter describes the structural, electronic, vibra...
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ژورنال
عنوان ژورنال: Toxicology Research
سال: 2013
ISSN: 2045-4538
DOI: 10.1039/c3tx50022e